Titelbild 6-Achsroboter von CHRONECT Quantos übernimmt Vial Transport


Powder dosing as a part of fully automated sample preparation.

Powder dosing in automatic sample preparation

A large number of substances are used in synthesis optimization. These substances are weighed in in the lower milligram range and passed on to the further experimental procedure. They are usually toxic or decompose in the ambient air, so that an enclosure under a protective atmosphere such as argon or helium is necessary. Manual weighing is complex and time-consuming.

The CHRONECT Quantos handles the weighing process for up to 32 powders in up to 288 1-mL vessels.

Advantages of fully automatic powder dosing at a glance

  • Integration of exact dosing and weighing technology from Mettler-Toledo
  • No manual handling of toxic substances
  • Automatic working under protective atmosphere possible
  • 32 solids and up to 288 target vessels
  • Data security through RFID chips
  • Connection of the emergency stop functions of the robot with safety options of the enclosure possible
  • Seamless documentation of every step and weigh-in
  • Connection to ELN systems possible
  • Different vessels can be used in one run

How it works

Up to 32 solids can be positioned on one shelf. These are stored in dosing heads. All information about the solid matter is stored on an RFID chip and read out via the shelf. Three SBS plates provide space for different vessel sizes in which the powders are weighed. Weighing takes place using the Quantos system from Mettler-Toledo. A six-axis robot transports the powder heads into the weighing system and prepares the vessels under the dosing head.

The CHRONOS software controls the system through a simple interface. Only the powders that are currently on the shelf are displayed. The SBS-plates are displayed pictorially. The user can now select the solid via a drop down menu. Following this, the user inserts the quantity to be dosed into the graphic of the plates. Simple functions, as known from Excel, facilitate the input into the cells and columns. All weights are documented.

Possible extension options

To increase the capacity of the target vessels, three additional SBS plates can be provided.

For substances that have to be stored in a sealed vessel, a CHRONECT Robotic with DeCapper module is a possible choice. The CHRONECT Robotic (xyz-Robot) offers modules for shaking, heating, filtration and solvent addition in addition to the storage option. This flexible unit is also controlled by the same software platform.
Funded innovation project

CHRONECT Quantos is a ZIM-funded project (Central Innovation Program for Medium-Sized Businesses) and was developed in a cooperation of Axel Semrau with Mettler-Toledo and Jüke Systemtechnik. At analytica 2018, CHRONECT Quantos was awarded the Application Award of LABORPRAXIS in the category laboratory technology.


Ein Graustufenbild von Janine Van den Haute

Do you have questions regarding the product? I would be glad to help you or to connect you with the right contact person.

Business Economist (VWA) Janine Schwafertz
Chromatography and Automatisation, Head of Order Processing
+49 2339 1209-57